Kinetics of wild type FXIa inhibition by ATIII and C1-INH in the absence of heparin. Recombinant FXIa (6 n m) was incubated at 37 °C with varying concentrations of ATIII ...
1. Vox Sang. 2012 Jan;102(1):40-6. doi: 10.1111/j.1423-0410.2011.01502.x. Epub 2011 May 5. Identification of kallikrein and FXIa as impurities in therapeutic ...
You have free access to this content Identification of kallikrein and FXIa as impurities in therapeutic immunoglobulins: implications for the safety and control of ...
In solution, and during contact activation in plasma, conversion of factor XI to factor XIa proceeds through an intermediate with one active site (1/2-FXIa).
Localization of ligand-binding exosites in the catalytic domain of FXIa and determination of the roles of calcium and the heavy chain of FXIa in fix activation by FXIa
FXIa and TF need not be present in quantifiable amounts to be useful as diagnostic markers. The methods described herein for determining the presence of FXIa or TF ...
Abstract. During surface-initiated blood coagulation in vitro, activated factor XII (fXIIa) converts factor XI (fXI) to fXIa. Whereas fXI deficiency is ...
FXIa G193E and FXIa WT Inhibition by AT and APPI—AT and APPI are two known physiologic inhibitors of FXIa. AT belongs to the serpin family of inhibitors and APPI to the ...