- FKBP38: A New Piece in the Apoptosis Puzzle
Apoptosis is essential for an organism's development, homeostasis, and protection from damaged cells. 1,2 There is more than one pathway by which apoptosis can occur ...
- Rheb Activates mTOR by Antagonizing Its Endogenous Inhibitor, FKBP38
Xiaochun Bai 1, 3, Dongzhu Ma 1, Anling Liu 1, Xiaoyun Shen 1, Qiming J ...
- FKBP38 - R&D Systems
FK506 Binding Proteins (FKBPs) are intracellular receptors for the immuno-suppressive drug FK506. The FKBP/FK506 complex exerts its immunosuppressive effects by ...
- Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin
Frank Edlich, 1 * Matthias Weiwad, 1 * Frank Erdmann, 1 Jörg Fanghänel, 1 Franziska Jarczowski, 1 Jens-Ulrich Rahfeld, 1 and Gunter Fischer 1 a
- Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to ...
Nature Cell Biology 5, 28 - 37 (2002) Published online: 23 December 2002 | doi:10.1038/ncb894. Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and ...
- Rheb Activates mTOR by Antagonizing Its Endogenous Inhibitor, FKBP38
Fig. 1. GTP-dependent interaction of Rheb with FKBP38. (A) Coimmunoprecipitation of FKBP38 with Rheb. Lysates from HEK293 cells were immunoprecipitated with antibody ...
- Co-chaperone FKBP38 Promotes HERG Trafficking
Valerie E. Walker, Roxana Atanasiu, Hung Lam and Alvin Shrier 1; Department of Physiology, McGill University ...
- Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein ...
Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38 *
- The Bcl-2 Regulator FKBP38-Calmodulin-Ca2+ Is Inhibited by Hsp90
Abstract. FKBP38 is a negative effector of the anti-apoptotic Bcl-2 protein in neuroblastoma cells. The interaction with Bcl-2 and the enzyme activity ...
- The Peptidyl Prolyl cis/trans Isomerase FKBP38 Determines Hypoxia ...
The Peptidyl Prolyl cis/trans Isomerase FKBP38 Determines Hypoxia-Inducible Transcription Factor Prolyl-4-Hydroxylase PHD2 Protein Stability